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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight-loss in addition to a reduced-calorie diet and physical activity.

    Using two separate drugs to shed pounds can be very effective you can find combinations before the FDA now awaiting approval. When dealing with fat loss and the those who go through it you need to err assisting caution and let the FDA do its job and demand some investigation be done so that the public is aware of the side effects and risks of the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say almost anything to keep people on their own medications.

    Researchers found out that participants investing in this drug to get a year, lost weight within 4 weeks and have kept the weight off through the entire 56 weeks from the study. Contrave can be a combination in the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which might be made up of many active ingredient, which can make them far better and safer.

    Combo-pilling is the newest fad or also the newest ahead under scrutiny and so it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular could be the fact that at the time of right now there are no long term prescription diet pills that have been authorized by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA.

    Seizures certainly are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug can also raise blood pressure and heartrate, and shouldn't be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must 't be used in patients with uncontrolled high hypertension, along with by you are not heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients having a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients to the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation.

    "There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.

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